रक्तशास्त्र
Hematology (BE: haematology) is the branch of internal medicine र pediatrics that is concerned with blood, the blood-forming organs र blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, र prevention of blood diseases.
Blood diseases affect the production of blood र its components, such as blood cells, hemoglobin, blood proteins, the mechanism of coagulation, etc.
विषयसूची |
Hematologists [सम्पादन गर्ने]
Medical doctors who work in hematology are known as hematologists. Their routine work may range from the management of the hematology laboratory, work at the microscope viewing blood films र bone marrow slides, interpretation of various hematology test results, care of in-patients र care of out-patients.
Hematologists may specialise further or have special interests, for example in:
- treating bleeding disorders such as hemophilia
- treating hematological malignacies such as lymphoma र leukemia (onco hematology)
- treating hemoglobinopathies
- in the science of blood transfusion र the work of a blood bank
Hematology as basic medical science [सम्पादन गर्ने]
- Blood
- Red blood cells
- Reticuloendothelial system
- Lymphatic system
- Blood transfusion
- Haemostasis
- Complement system
Classification of hematology diseases [सम्पादन गर्ने]
- Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
- Anemias (lack of red blood cells or hemoglobin)
- Iron deficiency anemia
- Megaloblastic anemia
- Vitamin B12 deficiency
- Folate deficiency
- Hemolytic anemias (destruction of red blood cells)
- Genetic disorders of RBC membrane
- Genetic disorders of RBC metabolism
- Immune mediated hemolytic anaemia (direct Coombs test is positive)
- Autoimmune hemolytic anemia
- Warm antibody autoimmune hemolytic anemia
- Idiopathic
- Systemic lupus erythematosus (SLE)
- Evans' syndrome (antiplatelet antibodies र haemolytic antibodies)
- Cold antibody autoimmune hemolytic anemia
- Warm antibody autoimmune hemolytic anemia
- Alloimmune hemolytic anemia
- Hemolytic disease of the newborn (HDN)
- Rh disease (Rh D)
- ABO hemolytic disease of the newborn
- Anti-Kell hemolytic disease of the newborn
- Rhesus c hemolytic disease of the newborn
- Other blood group incompatibility (RhC, Rhe, RhE, Kid, Duffy, MN, P र others)
- Hemolytic disease of the newborn (HDN)
- Drug induced immune mediated hemolytic anaemia
- Penicillin (high dose)
- Methyldopa
- Autoimmune hemolytic anemia
- Hemoglobinopathies (where these is an unstable or crystaline hemoglobin)
- Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
- Microangiopathic hemolytic anemia
- Aplastic anemia
- Decreased numbers of cells
- Myelodysplastic syndrome
- Myelofibrosis
- Neutropenia (decrease in the number of neutrophils)
- Agranulocytosis
- Glanzmann's thrombasthenia
- Thrombocytopenia (decrease in the number of platelets)
- Myeloproliferative disorders (Increased numbers of cells)
- Polycythemia vera (increase in the number of cells in general)
- Leukocytosis (increase in the number of white blood cells)
- Thrombocytosis (increase in the number of platelets)
- Myeloproliferative disorder
- Hematological malignancies
- Coagulopathies (disorders of bleeding र coagulation)
- Thrombocytosis
- Recurrent thrombosis
- Disseminated intravascular coagulation
- Disorders of clotting proteins
- Disorders of platelets
- Miscellaneous
- Haemotological changes secondary to non-haemotological disorders
Tests [सम्पादन गर्ने]
Tests used in the investigation of haematological problems include:
- Full blood count
- Erythrocyte sedimentation rate (ESR)
- Blood film
- Bone marrow biopsy
- Coombs test
- serum Ferritin level
- Vitamin B12 र Folate levels
- Prothrombin time
- Partial thromboplastin time
- Protein electrophoresis
- Hemoglobin electrophoresis
- D-dimer
Treatments [सम्पादन गर्ने]
Treatments include:
- Diet advice
- Oral medication - tablets or liquid medicines
- Anticoagulation therapy
- Intramuscular injections (for example, Vitamin B12 injections)
- Blood transfusion (for anemia)
- Venesection (for iron overload or polycythemia)
- Bone marrow transplant (for example, for leukemia)
- Chemotherapy (for example, for leukemia)
- Radiotherapy (in decline, for example, for leukemia)
Alphabetical lists [सम्पादन गर्ने]
External links [सम्पादन गर्ने]
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